There　is　growing　interest　about　the　conversion　of　lipids　to　renewable　fuels　as　the　alternatives　of　traditional　petroleum.　However,　the　development　of　efficient　catalysts　from　readily　available　materials　is　still　challenging.　In　this　study,　we　demonstrated　that　the　generation　of　diesel-like　fuel　from　methyl　palmitate　(MP)　through　catalytic　deoxygenation　could　be　significantly　promoted　by　modifying　the　ZrO2　support　with　B2O3,　a　cheap　and　readily　available　non-metal　oxide.　Characterization　results　showed　that　the　attaching　boron　atom　to　the　framework　of　ZrO2　support　to　form　the　B-O-Zr　interconnection　significantly　increased　the　acidic　site　concentration.　The　enhanced　acidity　of　B2O3/ZrO2　catalysts　afforded　the　improved　efficiency　for　MP　deoxygenation,　and　the　maximum　activity　was　obtained　at　a　B/Zr　molar　ratio　of　1/5　with　the　MP　conversion　of　86.6%　and　liquid　yield　of　69.3%.　The　effect　of　reaction　temperature　and　H2　pressure　on　the　MP　deoxygenation　performance　of　B2O3/ZrO2　catalysts　were　also　evaluated　systematically.　Combining　the　catalytic　and　spectroscopic　data,　it　revealed　that　the　MP　was　firstly　adsorbed　at　the　oxygen　vacancies　of　m-ZrO2　and　then　converted　to　＜　C15,　C15　alkane　and　alkenes　through　decarbonylation,　hydrocracking　and　dehydrogenation　reactions.