The　continuous　girder　bridge　is　the　main　type　of　small-　and　medium-sized　bridges;　however,　it　has　poor　collapse　resistance　and　suffers　frequent　earthquake　damage.　In　order　to　grasp　its　collapse　mechanism　and　clarify　the　internal　and　external　factors　affecting　its　collapse　resistance,　a　1:3-scaled,　two-span　bridge　model　subjected　to　shaking　table　test　research　was　taken　as　the　research　object.　The　factors　such　as　seismic　characteristics,　multi-directional　seismic　coupling,　span,　pier　height,　and　structural　system　type　were　analyzed　to　determine　the　influences　on　the　collapse　mode　of　the　bridge.　The　numerical　results　showed　that　different　ground　motion　characteristics　led　to　different　collapse　modes.　Vertical　ground　motion　had　little　effect　on　the　structural　response　of　the　bridge.　The　change　of　span　and　pier　height　significantly　changed　the　collapse　resistance.　A　seismic　isolation　design　could　improve　the　anti-collapse　performance,　but　the　collapse　mode　varied　with　the　system.　The　final　anti-collapse　design　suggestions　could　provide　reference　for　the　seismic　reinforcement　of　existing　continuous　girder　bridges　and　the　seismic　design　of　continuous　girder　bridges　that　will　be　constructed.