Recently,　polyoxoniobate-based　three-dimensional　framework　materials　have　been　a　research　hotspot　in　the　fields　of　inorganic　synthetic　chemistry　and　material　chemistry.　Such　materials　can　not　only　combine　the　excellent　properties　of　polyoxoniobate　with　the　advantages　of　the　frameworks,　but　also　exhibit　important　applications　in　photocatalysis,　host-guest　chemistry,　energy　conversion　and　so　on.　In　this　review,　the　recent　development　of　polyoxoniobate-based　three-dimensional　framework　materials　is　summarized,　including　their　assembly　methodologies,　structure　regulation,　properties,　and　related　applications.　Moreover,　the　current　challenges　and　the　prospects　of　these　materials　are　also　discussed.　©　2022,　Editorial　Department　of　Chem.　J.　Chinese　Universities.　All　right　reserved.