Neodymium (3+)-Coordinated Black Phosphorus Quantum Dots with Retrievable NIR/X-Ray Optoelectronic Switching Effect for Anti-Glioblastoma - Details

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Abstract：

Heteroatom　interaction　of　atomically　thin　nanomaterials　enables　the　improvement　of　electronic　transfer,　band　structure,　and　optical　properties.　Black　phosphorus　quantum　dots　(BP　QDs)　are　considered　to　be　candidate　diagnostic　and/or　therapeutic　agents　due　to　their　innate　biocompatibility　and　exceptional　photochemical　effects.　However,　BP　QDs　are　not　competitive　regarding　second　near-infrared　(NIR-II)　window　medical　diagnosis　and　X-ray　induced　phototherapy.　Here,　an　Nd3+　ion　coordinated　BP　QD　(BPNd)　is　synthesized　with　the　aim　to　sufficiently　improve　its　performances　in　NIR-II　fluorescence　imaging　and　X-ray　induced　photodynamic　therapy,　benefitting　from　the　retrievable　NIR/X-ray　optoelectronic　switching　effects　between　BP　QD　and　Nd3+　ion.　Given　its　ultrasmall　size　and　efficient　cargo　loading　capacity,　BPNd　can　easily　cross　the　blood–brain　barrier　to　precisely　monitor　the　growth　of　glioblastoma　through　intracranial　NIR-II　fluorescence　imaging　and　impede　its　progression　by　specific　X-ray　induced,　synergistic　photodynamic　chemotherapy.　©　2021　Wiley-VCH　GmbH

Keyword：

Biocompatibility Chemotherapy Diagnosis Fluorescence imaging Infrared devices Nanocrystals Neodymium compounds Optical properties Phosphorus Photodynamic therapy Semiconductor quantum dots

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[ 1 ] [Li, Zhi]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
[ 2 ] [Zhao, Caiyan]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
[ 3 ] [Fu, Qinrui]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
[ 4 ] [Ye, Jiamin]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
[ 5 ] [Su, Lichao]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
[ 6 ] [Ge, Xiaoguang]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
[ 7 ] [Chen, Lanlan]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
[ 8 ] [Song, Jibin]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
[ 9 ] [Yang, Huanghao]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou; 350108, China

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Small

ISSN： 1613-6810

Year： 2022

Issue： 5

Volume： 18

1 3 . 3

JCR@2022

1 3 . 0 0 0

JCR@2023

ESI HC Threshold：91

JCR Journal Grade：1

CAS Journal Grade：1

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WoS CC Cited Count：

SCOPUS Cited Count： 15

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 1

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