The　use　of　conjugated　microporous　polymers　(CMPs)　in　practical　wastewater　treatment　demands　further　design　on　the　pore　structure,　otherwise　their　adsorption　capacities　toward　heavy-metal　ions　were　moderate.　Here,　we　report　a　rational　design　approach,　which　produces　hybrid　molecular　pores　in　conjugated　microporous　poly(aniline)s　(CMPAs)　for　mercury　removal.　It　is　achieved　through　a　delicate　interval　introduction　of　linkers　with　differential　molecular　lengths　during　polymerization,　acquiring　both　diffusion　channels　and　storage　pores　for　radical　enhancement　of　mass　transfer　and　adsorption　storage.　The　resulting　CMPA-M　featured　a　large　adsorption　capacity　of　975　mg　g-1　and　rapid　kinetics　that　could　remove　94.8%　of　50　mg　g-1　of　mercury(II)　within　a　very　short　contact　time　of　48　s,　with　a　promising　initial　adsorption　rate　h　as　high　as　113　mg　g-1　min-1,　which　was　2.54-fold　larger　in　the　adsorption　capacity　and　45.2-fold　faster　in　the　adsorption　efficiency　compared　with　the　undeveloped　CMPAs.　More　importantly,　our　CMPA-M-2,　with　robust　stability　and　easy　reusability,　was　able　to　scavenge　over　99.9%　of　mercury(II)　from　the　actual　wastewater　in　a　harsh　condition　with　a　very　low　pH　of　0.77,　extremely　high　salinity　of　53,157　mg　L-1,　and　complex　impurities,　featuring　exceptional　selectivity　that　allows　us　to　extract　and　recycle　a　high　purity　of　99.1%　of　mercury　from　the　wastewater.　These　outcomes　demonstrate　the　unprecedented　potential　of　CMPs　for　environmental　remediation　and　real-world　mercury　extraction　and　present　benchmarks　for　CMP-based　mercury　adsorbents.　©　2021　American　Chemical　Society.