The　application　potential　of　Pt/Ti4O7　has　been　reported,　but　the　lack　of　research　on　the　relationship　between　Pt　loading,　MSI,　and　catalytic　activity　hinders　further　development.　Micron-sized　Ti4O7　powders　synthesized　by　a　thermal　reduction　method　under　an　H-2　atmosphere　were　used　as　a　support　material　for　Pt-based　catalysts.　Using　a　modified　polyol　method,　Pt/Ti4O7-5,　Pt/Ti4O7-10,　and　Pt/Ti4O7-20　with　different　mass　ratios　(Pt　to　Pt/Ti4O7　is　0.05,　0.1,　0.2)　were　successfully　synthesized.　Uniformly　dispersed　platinum　nanoparticles　exhibit　disparate　morphologies,　rod-like　for　Pt/Ti4O7-5　and　approximately　spherical　for　Pt/Ti4O7-10　and　Pt/Ti4O7-20.　Small-angle　deflections　and　lattice　reconstruction　induced　by　strong　metal-support　interactions　were　observed　in　Pt/Ti4O7-5,　which　indicated　the　formation　of　a　new　phase　at　the　interface.　However,　lattice　distortions　and　dislocations　for　higher　loading　samples　imply　the　existence　of　weak　metal-support　interactions.　A　possible　mechanism　is　proposed　to　explain　the　different　morphologies　and　varying　metal-support　interactions　(MSI).　With　X-ray　photoelectron　spectroscopy,　spectrums　of　Pt　and　Ti　display　apparent　shifts　in　binding　energy　compared　with　commercial　Pt-C　and　non-platinized　Ti4O7,　which　can　properly　explain　the　changes　in　absorption　ability　and　oxygen　reduction　reaction　activity,　as　described　in　the　electrochemical　results.　The　synthetic　method,　Pt　loading,　and　surface　coverage　of　the　support　play　an　important　role　in　the　adjustment　of　MSI,　which　gives　significant　guidance　for　better　utilizing　MSI　to　prepare　the　target　catalyst.