Direct C-H functionalization of tetrahydro-γ-carbolines at the α-position - Details

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The　direct　C-H　functionalization　of　tetrahydro-γ-carbolines　(THγCs)　at　the　α-position　has　been　presented.　This　mild　and　simple　strategy　allows　coupling　of　THγCs　with　various　anilines　and　indoles　with　satisfactory　to　excellent　yields.　This　two-step/one-pot　method　could　be　applied　to　synthesize　complex　compounds　and　is　suitable　for　the　C-H　functionalization　of　similar　biologically　active　structures.　©　2022　The　Royal　Society　of　Chemistry.

Keyword：

Aniline

Community：

[ 1 ] [Zhang, Yahui]Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, FuZhou University, Fuzhou, Fujian; 350116, China
[ 2 ] [Chen, Yi]Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, FuZhou University, Fuzhou, Fujian; 350116, China
[ 3 ] [Guo, Mei]Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, FuZhou University, Fuzhou, Fujian; 350116, China
[ 4 ] [Sun, Ge]Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, FuZhou University, Fuzhou, Fujian; 350116, China
[ 5 ] [Que, Rongbin]Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, FuZhou University, Fuzhou, Fujian; 350116, China
[ 6 ] [Cui, Ranran]Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, FuZhou University, Fuzhou, Fujian; 350116, China
[ 7 ] [Gao, Yu]Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, FuZhou University, Fuzhou, Fujian; 350116, China
[ 8 ] [Chen, Haijun]Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, FuZhou University, Fuzhou, Fujian; 350116, China

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Source ：

New Journal of Chemistry

ISSN： 1144-0546

Year： 2022

Issue： 20

Volume： 46

Page： 9511-9514

3 . 3

JCR@2022

2 . 7 0 0

JCR@2023

ESI HC Threshold：74

JCR Journal Grade：2

CAS Journal Grade：3

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ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 1

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