In　this　study,　Ni-metal-organic　frameworks　(MOFs)　were　used　as　precursors　to　obtain　carbon-supported　nickel　composites　(Ni@C)　after　calcination.　The　hydrodeoxygenation　properties　of　the　model　compound　and　corncob　lignin　were　investigated　without　an　external　hydrogenation　source　and　initial　pressure.　Additionally,　the　effect　of　Ni@C　on　degradation　of　model　compounds,　corncob　lignin,　and　benzyl　phenyl　ether　(BPE)　under　different　conditions　was　examined.　The　results　showed　that　with　isopropanol　as　the　in　situ　hydrogen　source,　the　conversion　percentage　of　BPE　was　90.2%　and　the　yield　of　phenol　was　88.3　wt　%　at　150　°C.　The　catalysts　were　characterized　by　scanning　electron　microscopy　(SEM),　X-ray　diffraction　(XRD),　NH3　temperature-programmed　desorption　(NH3-TPD),　X-ray　photoelectron　spectroscopy　(XPS),　and　thermogravimetry　(TG),　and　the　lignin　and　bio-oil　were　characterized　by　gas　chromatography-mass　spectrometry　(GC-MS)　and　two-dimensional　heteronuclear　single　quantum　coherence　(2D-HSQC).　It　was　found　that　the　Ni@C　catalyst　with　well　dispersion,　high　support　rate,　and　rich　acid　sites　was　successfully　synthesized.　In　the　process　of　degradation,　the　C-O　ether　bond　in　the　structure　of　lignin　was　successfully　broken　to　generate　the　phenolic　monomer,　and　the　high-efficiency　hydrodeoxygenation　of　lignin　was　realized　under　mild　conditions.　©　2022　American　Chemical　Society.