In　this　study,　we　reported　that　flash　sintering　(FS)　could　be　efficiently　triggered　at　room　temperature　(25　°C)　by　manipulating　the　oxygen　concentration　within　ZnO　powders　via　a　versatile　defect　engineering　strategy,　fully　demonstrating　a　promising　method　for　the　repaid　prototyping　of　ceramics.　With　a　low　concentration　of　oxygen　defects,　FS　was　only　activated　at　a　high　onset　electric　field　of　∼2.7　kV/cm,　while　arcs　appearing　on　the　surfaces　of　samples.　Strikingly,　the　onset　electric　field　was　decreased　to　©　2022,　The　Author(s).