The　development　of　mixed-linker　metal-organic　frameworks　(MOFs)　is　an　efficient　strategy　to　improve　the　performance　of　MOFs.　Herein,　we　successfully　integrate　tetrakis(4-carboxyphenyl)porphyrin　(TCPP)　into　different　Zr-MOFs　via　a　facile　one-pot　solvothermal　synthesis　while　preserving　the　integrity　of　their　frameworks.　The　functional　groups,　length　of　primary　linkers,　and　the　inner　pore　structure　significantly　affected　the　properties　of　the　synthesized　TCPP@MOFs,　such　as　surface　area,　average　pore　size,　and　O-1(2)　productivity.　Among　them,　TCPP@PCN-777　demonstrated　the　largest　surface　area　(2386　cm(2)/g,　as　measured　by　N-2　uptake)　and　the　highest　O-1(2)　generation　rate　(1.15　h(-1),　[O-1(2)](ss)　=　2.66　X　10(-12)　M)　under　irradiation.　The　TCPP　loading　was　also　shown　to　affect　the　crystal　phase,　morphology,　surface　area,　and　photochemical　properties　of　the　synthesized　MOFs.　Therefore,　TCPP@PCN-777s　with　various　TCPP　loadings　were　synthesized　to　investigate　the　optimum　loading.　The　optimized　TCPP@MOF,　TCPP@PCN-777-30,　was　evaluated　for　its　removal　of　model　contaminant　ranitidine　(RND)　through　both　adsorption　and　photodegradation.　TCPP@PCN-777-30　showed　a　higher　adsorption　capacity　toward　RND　than　both　the　parent　MOF　(PCN-777)　and　commercially　available　activated　carbon,　and　effectively　degraded　RND　in　aqueous　solution　(＞99%　photodegradation　in　1　h).　With　irradiation,　TCPP@PCN-777-30　showed　a　minimal　loss　in　adsorption　efficiency　over　four　consecutive　treatment　cycles,　confirming　the　reusability　of　the　material　enabled　through　the　incorporation　of　TCPP　into　the　MOF　structure.　This　work　not　only　developed　an　efficient　multifunctional　material　for　environmental　remediation　but　also　forwarded　knowledge　on　the　effect　of　linker　environment　(i.e.,　functional　groups,　framework　structure,　and　linker　ratio)　on　the　properties　of　TCPP@MOFs　to　guide　future　research　on　mixed-linker　MOFs.