The　realization　of　solar-driven　photoelectrochemical　(PEC)　process　lies　in　the　success　development　of　materials　with　excellent　photoelectric　properties.　Past　reports　identified　TiO2,　upon　modified　with　both　Cd　and　ZnIn2S4　(ZIS),　exhibits　promising　PEC　performance;　however,　at　the　cost　of　tedious　preparation.　In　view　of　this,　our　work　proposes　a　facile　one-step　hydrothermal　strategy　to　deposit　both　modifiers　onto　the　pre-obtained　TiO2　nanotubes　(NTs),　realizing　rose-like　TiO2/ZnIn2S4　(TiO2/ZIS)　or　tremella-like　TiO2/Cd:ZnIn2S4　(TiO2/Cd:ZIS)　with　improved　PEC　performances.　Interestingly,　the　thickness　of　ZIS　petals,　which　deposited　on　top　of　TiO2　NTs,　is　positively-correlated　to　its　Cd-composition,　signifying　the　substitutional　doping　of　Cd　into　the　unit　cell　of　ZIS.　This　renders　robust　ionic　interactions　between　the　constituents,　prompting　the　enhanced　optical　properties　of　TiO2　in　conjecture　to　its　reduced　impedance.　As　a　result,　the　recombination　rate　of　photo-electric-derived　carriers　was　drastically　suppressed,　with　an　improved　photocurrent　density　of　606.2　mu　A　cm(-2)　recorded　by　TiO2/Cd:ZIS　photoanode　under　solar　irradiation.　Such　performance　is　80　times　and　5.16　times　higher　than　those　of　bare　TiO2　NTs　and　TiO2/ZIS　counterparts.　The　photoconversion　efficiencies　in　terms　of　incident　photon-to-current　conversion　efficiency　(IPCE)　and　applied　bias　photon　current　efficiency　(ABPE)　for　TiO2/Cd:ZIS　were　significantly　improved　too,　recorded　at　1.12%　and　0.38%,　respectively,　under　standard　evaluation　condition.　As　summary,　our　work　proposes　a　facile　one-step　hydrothermal　approach　that　simultaneously-deposit　both　Cd　and　ZIS　onto　TiO2　photoanode　for　an　enhanced　PEC　performance.　This　opens　up　a　wider　horizon　for　PEC　technology,　further　unlocking　its　potential　in　both　energy　and　environmental　applications.