With　the　rapid　development　of　nanotechnology　and　laser　technology,　surface-enhanced　Raman　scattering　(　SERS)　technology　has　flourished　with　a　great　leap.　As　an　analysis　and　detection　technology　for　fast,　nondestructive,　and　ultra-　sensitive　response　to　the　fingerprint　information　of　the　target　molecule,　SERS　technology　has　been　widely　applied　in　the　field　of　food　detection,　environmental　monitoring　and　clinical　diagnosis.　Fabrication　of　SERS　substrate　is　the　committed　step　of　achieving　the　ultra-　sensitive　detection　in　various　fields　using　SERS　technology.　At　present,　the　SERS　activity,　homogeneity,　and　other　properties　of　SERS　substrates　which　are　constructed　by　single　noble　metal　nanomaterials　through　complex　and　timeconsuming　methods　cannot　fit　the　demand　of　the　point-of-care　detection　in　various　fields.　Therefore,　more　and　more　research　scholars　focus　on　the　development　of　simple　and　rapid　methods　to　fabrication　of　multi-functional　composite　SERS　substrates　and　application　of　these　composite　SERS　substrates　into　the　field　of　food　detection,　environmental　monitoring　and　clinical　diagnosis.　This　article　mainly　reviews　the　preparation　of　precious　metal　composite　SERS　substrates　and　their　applications　in　the　past　years,　discusses　and　analyzes　the　function　and　application　advantages　of　multi-functional　composite　SERS　substrates.　The　forecast　of　multi-functional　composite　SERS　substrate　is　also　provided　at　the　end　of　this　article.