The　search　for　feasible　strategies　to　construct　molecular　materials　whose　physical　properties　can　be　mod-ulated　dynamically　by　external　stimuli,　especially　light　for　sunlight　is　the　cleanest　and　most　abundantly　renewable　energy　source,　has　attracted　increasing　attention　owing　to　their　promising　application　in　the　field　of　detection,　photo-electronic　devices,　information　storage,　etc.　As　a　key　branch,　crystalline　pho-tochromic　materials　are　usually　formed　by　the　combination　of　organic　photoresponsive　molecules　and　inorganic　functional　units.　Under　the　stimuli　of　light,　the　changes　of　structures　and　some　physical　prop-erties　could　occur,　which　provides　a　platform　to　develop　photoswitching　smart　materials.　To　further　pro-mote　the　understanding　and　development　of　crystalline　photochromic　materials,　in　this　review,　we　mainly　focus　on　the　representative　smart　photochromic　hybrids　with　fast　and　stable　multi-stimuli　responsive　behavior　or　with　various　switchable　functions.　In　detail,　in　the　first　unit,　the　common　design　and　synthesis　strategy　of　crystalline　photoresponsive　materials　will　be　demonstrated.　The　second　section　will　introduce　photochromic　hybrids　with　novel　structures　and　enhanced　performance　(multi-stimuli　responsive,　responsive　rate).　And　the　third　section　will　present　photochromic　hybrids　with　photo-modulated　luminescence　(fluorescence,　phosphorescence),　photomagnetism,　photoconductivity,　pho-tothermal　conversion,　or　photoswitchable　gas　uptake　behavior.　Finally,　the　future　challenges　and　oppor-tunities　for　the　development　of　photoresponsive　smart　hybrids　will　be　addressed.　(c)　2022　Elsevier　B.V.　All　rights　reserved.