Highly　sensitive　pressure　sensors　are　often　deployed　in　human-machine　interaction　area,　touch　screen　and　human　motion　detection.　However,　there　are　still　great　challenges　to　fabricating　with　high　sensitivity　pressure　sensor　with　wide-range　detection.　Herein,　we　developed　a　new　strategy　to　fabricate　a　highly　sensitive　pressure　sensor　using　sandpaper　and　improve　its　detection　range　using　a　sacrificial　template.　It　was　the　fthatirst　time　to　combine　microstructure　processing　with　the　sacrificial　template　method　to　fabricate　pressure　sensor.　The　microstructure　of　sandpaper　endowed　the　sensor　with　high　sensitivity,　and　the　elastic　substrate　enhanced　the　sensor　ability　to　resist　high　pressure　without　being　damaged.　The　fabricated　sensor　device　exhibits　a　superior　sensitivity　of　39.077　kPa−1　in　the　range　from　50　kPa　to　110　kPa　with　a　broad　linear　response.　Remarkably,　high　pressure　ceiling　(<160　kPa)　ensures　that　the　sponge　could　be　applied　in　different　practical　conditions　to　monitor　a　range　of　subtle　human　motions　including　finger,　wrist　bending,　and　pulse.　For　applications,　the　sensor　device　can　not　only　detect　the　foot　stepping　behavior　(0.7　MPa)　but　also　produce　an　obvious　response　to　an　extremely　slight　paper　(9　mg,　∼0.9　Pa).　The　successful　preparation　of　this　micro-structured　elastic　sponge　material　provided　new　ideas　for　exploring　its　potential　applications　in　pressure　sensors　and　flexible　wearable　electronic　devices.　©　2022