As　non-renewable　cultural　heritage,　wall　paintings　play　an　important　role　in　society.　To　reveal　the　trends　in　the　scientific　analysis　of　mural　paintings,　845　relevant　research　articles　published　from　2011　to　2021　were　collected　from　the　Web　of　Science　database　and　analyzed.　The　VOSviewer　software　was　adopted　to　map　the　network　data　of　scientific　publications,　so　that　relationships　among　authors,　countries,　institutions　can　be　displayed,　and　the　co-occurrence　of　keywords　and　co-citation　can　be　analyzed.　The　results　revealed　close　and　strong　interconnections　between　the　top　authors,　suggesting　a　considerable　strong　research　link　in　this　field.　The　cooperation　between　research　institutions　was　relatively　close.　The　most　productive　country　of　relevant　publications　was　Italy.　The　leading　journals　for　the　scientific　analysis　of　wall　paintings　were　Journal　of　Raman　Spectroscopy　and　Journal　of　Cultural　Heritage.　At　present,　the　hotspots　of　scientific　analysis　and　research　on　wall　painting　are　revealing　the　composition,　distribution,　origin,　and　deterioration　mechanism　of　pigments,　alongside　with　evaluating　the　effects　and　mechanism　of　conservation　materials　and　techniques.　On　the　one　hand,　a　possible　development　direction　in　this　field　is　introducing　more　cutting-edge　analysis　and　data　processing　methods.　On　the　other　hand,　scientific　analysis　is　increasingly　adopted　to　guide　the　research　and　development　of　mural　conservation　materials.　©　2022,　The　Author(s).