Proper　amount　of　fluorion　is　very　important　to　human　health,　but　excessive　fluorion　is　harmful.　Therefore,　the　content　of　fluorion　in　tap　water　is　strictly　required　to　be　controlled　within　a　certain　range.　Here,　we　propose　the　first　colorimetric　and　fluorescence　enhanced　sensor　to　detect　fluorion　with　high　selectivity.　The　classic　MOF　material　UiO-66　is　combined　with　fluorescent　dye　FITC　to　form　a　nano-system.　When　there　is　fluorion,　which　will　be　combined　with　UiO-66　and　FITC,　respectively,　to　achieve　colorimetric　and　fluorescence　enhancement.　It　has　a　good　linear　relationship　in　the　range　of　2-150　mu　M　(0.038-2.85　ppm),　and　has　been　applied　to　the　detection　of　actual　water　samples.　The　field　visual　detection　of　fluoride　ion　is　realized,　and　the　application　of　MOF　in　the　field　of　fluorescence　sensing　is　broadened.