Electrochemical　point-of-care　testing　(POCT)　technology　is　widely　used　in　clinical　testing,　health　management,　epidemic　control,　food　safety　monitoring,　and　drug　detection.　Existing　electrochemical　POCT　devices　are　mostly　single-channel　tests　with　a　simple　detection　index,　fixed　sensitivity,　and　limited　test　range.　In　this　article,　a　dual-channel,　high-precision　electrochemical　device　with　automatic　analytic　software　is　developed.　Two　independent　channels　with　consistent　performance　can　be　operated　at　the　same　time,　multiplying　the　detection　efficiency.　The　digital　potentiometer　is　adopted　as　the　feedback　resistor　for　the　operational　amplifier,　and　an　automatic　adjustment　program　is　set　up　on　the　smartphone　app　to　achieve　automatic　adjustment　of　current　detection　sensitivity.　An　automatic　peak-seeking　function　is　proposed,　which　can　quickly　locate　and　record　the　peak　voltage　and　current.　The　current　detection　range　from　±10　nA　to　±2　mA　with　a　sensitivity　up　to　10-8A　and　a　current　detection　resolution　as　low　as　0.062%　(6.19　pA　in　the　±10　nA　range)　are　obtained.　The　device　has　been　carried　out　for　the　simultaneous　detection　of　ascorbic　acid　(AA),　uric　acid　(UA),　and　dopamine　(DA)　(R2　＞0.977).　The　results　indicate　that　the　dual-channel　device　is　of　wide　linear　detection　range,　high　precision,　and　consistency.　It　provides　a　technical　means　and　a　test　platform　for　accurate　and　timely　diagnosis　of　relevant　diseases　and　health　monitoring.　©　2001-2012　IEEE.