Fluorinated　organoboron　compounds　are　important　synthetic　building　blocks　that　combine　the　unique　characteristics　of　a　fluorinated　motif　with　the　versatile　synthetic　applications　of　organoboron　moiety.　This　review　article　guides　the　research　on　fluorinated　organoboron　compounds　mainly　from　four　aspects　in　recent　years:　selective　monodefluoroborylation　of　polyfluoroarenes　and　polyfluoroalkenes,　selective　borylation　of　fluorinated　substrates,　selective　fluorination　of　organoboron　compounds,　and　borofluorination　of　alkynes/olefins.　In　addition,　this　review　will　provide　a　necessary　guidance　and　inspiration　for　the　research　on　the　valuable　synthetic　building　block　fluorinated　organoboron　compounds.　©　2022　American　Chemical　Society.　All　rights　reserved.