Substituted　quinolin-3-amines　are　essential　cores　of　many　natural　products　and　bioactive　molecules.　Here,　an　expedient　method,　which　employed　1,2,3,5-tetrakis(carbazol-9-yl)4,6-dicyanobenzene　(4CzIPN)　as　a　photocatalyst　to　realize　the　radical-initiated　cascade　cyclization　reaction　of　isocyanides,　was　developed　for　the　synthesis　of　quinolin-3-amines.　A　wide　range　of　polysubstituted　quinolin-3-amines　were　successfully　constructed　in　moderate　to　good　yields.　©　2023　The　Royal　Society　of　Chemistry.