In　this　study,　based　on　soybean　urease　and　standard　sand,　the　unconfined　compressive　strength　test　and　permeability　test　of　four　variables　of　urease　concentration,　urea　concentration,　calcium　chloride　concentration　and　sodium　alginate　content　under　different　combinations　of　values　were　carried　out,　and　the　range　analysis　and　variance　analysis　of　test　data　were　carried　out.　On　this　basis,　the　coupling　model　of　unconfined　compressive　strength　and　permeability　coefficient　of　soybean　urease　reinforced　sand　was　established　based　on　four　test　variables.　It　was　found　that　the　engineering　characteristics　of　soybean　urease　reinforced　sand　were　significantly　affected　by　the　combination　of　variable　values.　The　maximum　value　of　unconfined　compressive　strength　under　the　test　combination　condition　was　6.5　times　of　the　minimum　value,　and　the　minimum　value　of　permeability　coefficient　was　only　1/4　of　the　maximum　value.　The　primary　and　secondary　order　of　influence　variables　of　unconfined　compressive　strength　was:　urea　concentration　＞　calcium　chloride　concentration　＞　urease　concentration　＞　sodium　alginate　content,　and　the　primary　and　secondary　order　of　influence　variables　of　permeability　coefficient　was:　urea　concentration　＞　calcium　chloride　concentration　＞　sodium　alginate　content　＞　urease　concentration.　The　influence　of　urea　concentration　on　unconfined　compressive　strength　and　permeability　coefficient　was　obvious,　and　the　influence　of　the　other　three　variables　was　not　obvious.　In　addition,　it　was　confirmed　that　the　established　coupling　model　of　unconfined　compressive　strength　and　permeability　coefficient　of　soybean　urease　reinforced　sand　had　high　correlation　coefficient　and　significant　linear　regression,　which　can　be　used　for　subsequent　research　and　engineering　application.　©　2023,　Korean　Society　of　Civil　Engineers.