As　an　emerging　micro-pollutant,　p-arsanilic　acid　(p-ASA)　exist　widely　in　the　environment,　and　it　can　form　highly　toxic　arsenate　and　arsenite　during　the　migration　and　transformation　process,　which　greatly　increases　the　risk　of　arsenic　pollution　in　the　ecosystem.　Additionally,　three-dimensional　(3D)　porous　block　materials　have　the　advantage　of　stronger　adsorption　performance,　faster　adsorption　rate　and　easy　recovery,　showing　broad　application　prospects　in　water　pollution　control.　Hence,　the　aminozed　collagen　fibers　foam　(ACFF)　with　3D　porous　block　structure　was　synthesized.　The　maximum　adsorption　capacity　of　ACFF　for　p-ASA　was　476.19　mg·g−1　due　to　the　rich　honeycomb　porous　structure　and　the　synergistic　effect　of　electrostatic　attraction,　hydrogen　bonding　effect　and　amphiphilicity.　Moreover,　ACFF　is　not　only　easy　to　recycle,　but　also　has　good　elastic　recovery　and　regeneration　performance.　The　pore　size　of　ACFF　was　concentrated　in　the　range　of　25–5000　nm,　and　the　porosity　was　71.66%.　ACFF　may　be　an　adsorbent　with　great　potential　for　the　removal　of　organoarsenic　contaminants　in　water.　©　2023　The　Institution　of　Chemical　Engineers