The　problems　of　easy　oil　contamination,　easy　oxidation,　and　low　dye　removal　ability　of　2D　MXene　hinder　its　practical　application　in　high-efficiency　oil/water　separation　and　dye　removal.　In　this　study,　Ti3C2Tx　was　first　modified　using　NH3·H2O　to　obtain　intercalated　Ti3C2Tx　(TN),　and　then,　N-[3-(trimethoxysilyl)　propyl]　ethylenediamine　(AEAPTMS)　was　used　to　conduct　the　surface　aminated-modification　of　TN　to　achieve　functional　Ti3C2Tx　(TN-AEAPTMS),　which　was　then　loaded　onto　polyurethane　(PU)　sponge　to　get　TN-AEAPTMS@PU　sponge.　The　low　oil　adhesion　and　super　hydrophilicity/underwater　super　oleophobicity　of　TN-AEAPTMS@PU　sponge　enable　excellent　separation　performance　for　oil/water　mixtures　of　different　densities.　After　being　soaked　in　water　for　45　days,　TN-AEAPTMS　can　still　maintain　its　original　accordion-like　morphology　and　hold　good　oil/water　separation　performance,　overcoming　the　performance　degradation　caused　by　easy　oxidation　of　Ti3C2Tx　under　water.　More　importantly,　TN-AEAPTMS@MCE,　which　is　acquired　through　vacuum　suction　filtration　with　TN-AEAPTMS　loaded　onto　mixed　cellulose　ester　microporous　membrane,　can　remove　various　anionic　and　cationic　organic　dyes　with　high　flux　and　removal　rate,　innovatively　overcoming　the　poor　adsorption　performance　of　Ti3C2Tx　for　anionic　dyes.　Therefore,　the　TN-AEAPTMS　composite　exhibits　excellent　potential　for　practical　applications　in　oil/water　separation　and　dye　removal.　©　2023　The　Royal　Society　of　Chemistry.