Membrane　separation　strategies　offer　promising　platform　for　the　emulsion　separation.　However,　the　low　mechanical　strength　of　membrane　separation　layers　and　the　trade-off　between　separation　flux　and　efficiency　present　significant　challenges.　In　this　study,　we　report　a　CFM@UiO-66-NH2　membrane　with　high　separation　flux,　efficiency　and　stability,　through　utilizing　a　robust　anti-abrasion　collagen　fiber　membrane　(CFM)　as　the　multifunctional　support　and　UiO-66-NH2　by　an　in-situ　growth　as　the　separation　layer.　The　high　mechanical　strength　of　the　CFM　compensated　for　the　weakness　of　the　separation　layer,　while　the　charge-breaking　effect　of　UiO-66-NH2,　along　with　the　size　sieving　of　its　constituent　separating　layers　and　the　capillary　effect　of　the　collagen　fibers,　contributed　to　the　potential　for　efficient　separation.　Additionally,　the　CFM@UiO-66-NH2　membrane　exhibited　superhydrophilic　properties,　making　it　suitable　for　separating　oil-in-water　microemulsions　and　nanoemulsions　stabilized　by　anionic　surfactants.　The　membrane　demonstrated　remarkable　separation　efficiencies　of　up　to　99.960%　and　a　separation　flux　of　370.05　L·m−2·h−1.　Moreover,　it　exhibits　stability,　durability,　and　abrasion　resistance,　maintaining　excellent　separation　performance　even　when　exposed　to　strong　acids　and　alkalis　without　any　damage　to　its　structure　and　performance.　After　six　cycles　of　reuse,　it　achieved　a　separation　flux　of　417.97　L·m−2·h−1　and　a　separation　efficiency　of　99.747%.　Furthermore,　after　undergoing　500　cycles　of　strong　abrasion,　the　separation　flux　remained　at　124.39　L·m−2·h−1,　with　a　separation　efficiency　of　99.992%.　These　properties　make　it　suitable　for　the　long-term　use　in　harsh　operating　environments.　We　attribute　these　properties　to　the　electrostatic　effect　resulting　from　the　amino　group　on　UiO-66-NH2　and　its　in-situ　growth　on　the　CFM,　which　forms　a　size-screening　separation　layer.　Our　work　highlights　the　potential　of　the　CFM@UiO-66-NH2　membrane　as　an　environmentally　friendly　size-screening　material　for　the　efficient　emulsion　wastewater　separation.　©　2023　The　Chemical　Industry　and　Engineering　Society　of　China,　and　Chemical　Industry　Press　Co.,　Ltd