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author：

Li, H. (Li, H..) [1] | Wu, S. (Wu, S..) [2] | Li, J. (Li, J..) [3] | Xiong, Z. (Xiong, Z..) [4] | Yang, K. (Yang, K..) [5] | Ye, W. (Ye, W..) [6] | Ren, J. (Ren, J..) [7] | Wang, Q. (Wang, Q..) [8] | Xiong, M. (Xiong, M..) [9] | Zheng, Z. (Zheng, Z..) [10] | Zhang, S. (Zhang, S..) [11] | Han, Z. (Han, Z..) [12] | Yang, P. (Yang, P..) [13] | Jiang, B. (Jiang, B..) [14] | Ping, J. (Ping, J..) [15] | Zuo, Y. (Zuo, Y..) [16] | Lu, X. (Lu, X..) [17] | Zhai, Q. (Zhai, Q..) [18] | Yan, H. (Yan, H..) [19] | Wang, S. (Wang, S..) [20] | Ma, S. (Ma, S..) [21] | Zhang, B. (Zhang, B..) [22] | Ye, J. (Ye, J..) [23] | Qu, J. (Qu, J..) [24] | Yang, Y.-G. (Yang, Y.-G..) [25] | Zhang, F. (Zhang, F..) [26] | Liu, G.-H. (Liu, G.-H..) [27] | Bao, Y. (Bao, Y..) [28] | Zhang, W. (Zhang, W..) [29]

Indexed by：

Scopus

Abstract：

Diverse　individuals　age　at　different　rates　and　display　variable　susceptibilities　to　tissue　aging,　functional　decline　and　aging-related　diseases.　Centenarians,　exemplifying　extreme　longevity,　serve　as　models　for　healthy　aging.　The　field　of　human　aging　and　longevity　research　is　rapidly　advancing,　garnering　significant　attention　and　accumulating　substantial　data　in　recent　years.　Omics　technologies,　encompassing　phenomics,　genomics,　transcriptomics,　proteomics,　metabolomics　and　microbiomics,　have　provided　multidimensional　insights　and　revolutionized　cohort-based　investigations　into　human　aging　and　longevity.　Accumulated　data,　covering　diverse　cells,　tissues　and　cohorts　across　the　lifespan　necessitates　the　establishment　of　an　open　and　integrated　database.　Addressing　this,　we　established　the　Human　Aging　and　Longevity　Landscape　(HALL),　a　comprehensive　multi-omics　repository　encompassing　a　diverse　spectrum　of　human　cohorts,　spanning　from　young　adults　to　centenarians.　The　core　objective　of　HALL　is　to　foster　healthy　aging　by　offering　an　extensive　repository　of　information　on　biomarkers　that　gauge　the　trajectory　of　human　aging.　Moreover,　the　database　facilitates　the　development　of　diagnostic　tools　for　aging-related　conditions　and　empowers　targeted　interventions　to　enhance　longevity.　HALL　is　publicly　available　at　https://ngdc.cncb.ac.cn/hall/index.　©　The　Author(s)　2023.　Published　by　Oxford　University　Press　on　behalf　of　Nucleic　Acids　Research.

Keyword：

Community：

  • [ 1 ] [Li H.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 2 ] [Li H.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 3 ] [Wu S.]CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 4 ] [Wu S.]National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 5 ] [Wu S.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 6 ] [Li J.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 7 ] [Li J.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 8 ] [Xiong Z.]Interdisciplinary Institute for Medical Engineering, Fuzhou University, Fuzhou, 350002, China
  • [ 9 ] [Yang K.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 10 ] [Yang K.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 11 ] [Yang K.]Sino-Danish College, University of Chinese Academy of Sciences, Beijing, 101408, China
  • [ 12 ] [Ye W.]Department of Vascular Surgery, Quzhou Affiliated Hospital of Wenzhou Medical University, Beijing, 100101, China
  • [ 13 ] [Ye W.]The Joint Innovation Center for Engineering in Medicine, Quzhou Affiliated Hospital of Wenzhou Medical University, 324000, China
  • [ 14 ] [Ren J.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 15 ] [Ren J.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 16 ] [Ren J.]Sino-Danish College, University of Chinese Academy of Sciences, Beijing, 101408, China
  • [ 17 ] [Ren J.]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China
  • [ 18 ] [Wang Q.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 19 ] [Wang Q.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 20 ] [Xiong M.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 21 ] [Xiong M.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 22 ] [Zheng Z.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 23 ] [Zheng Z.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 24 ] [Zhang S.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 25 ] [Zhang S.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 26 ] [Han Z.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 27 ] [Han Z.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 28 ] [Yang P.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 29 ] [Yang P.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 30 ] [Jiang B.]Department of Vascular Surgery, Quzhou Affiliated Hospital of Wenzhou Medical University, Beijing, 100101, China
  • [ 31 ] [Ping J.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 32 ] [Ping J.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 33 ] [Zuo Y.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 34 ] [Zuo Y.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 35 ] [Lu X.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 36 ] [Lu X.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 37 ] [Zhai Q.]Department of Vascular Surgery, Quzhou Affiliated Hospital of Wenzhou Medical University, Beijing, 100101, China
  • [ 38 ] [Yan H.]Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu HospitalCapital Medical University, Beijing, 100053, China
  • [ 39 ] [Yan H.]Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China
  • [ 40 ] [Wang S.]Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu HospitalCapital Medical University, Beijing, 100053, China
  • [ 41 ] [Wang S.]Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China
  • [ 42 ] [Wang S.]Aging Biomarker Consortium, Beijing, 100101, China
  • [ 43 ] [Ma S.]State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China
  • [ 44 ] [Ma S.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 45 ] [Ma S.]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China
  • [ 46 ] [Ma S.]Aging Biomarker Consortium, Beijing, 100101, China
  • [ 47 ] [Zhang B.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 48 ] [Ye J.]Department of Vascular Surgery, Quzhou Affiliated Hospital of Wenzhou Medical University, Beijing, 100101, China
  • [ 49 ] [Qu J.]State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China
  • [ 50 ] [Qu J.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 51 ] [Qu J.]Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China
  • [ 52 ] [Qu J.]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China
  • [ 53 ] [Qu J.]Aging Biomarker Consortium, Beijing, 100101, China
  • [ 54 ] [Yang Y.-G.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 55 ] [Yang Y.-G.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 56 ] [Yang Y.-G.]Sino-Danish College, University of Chinese Academy of Sciences, Beijing, 101408, China
  • [ 57 ] [Zhang F.]The Joint Innovation Center for Engineering in Medicine, Quzhou Affiliated Hospital of Wenzhou Medical University, 324000, China
  • [ 58 ] [Liu G.-H.]State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China
  • [ 59 ] [Liu G.-H.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 60 ] [Liu G.-H.]Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, 100101, China
  • [ 61 ] [Liu G.-H.]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China
  • [ 62 ] [Liu G.-H.]Advanced Innovation Center for Human Brain Protection, National Clinical Research Center for Geriatric Disorders, Xuanwu HospitalCapital Medical University, Beijing, 100053, China
  • [ 63 ] [Liu G.-H.]Aging Translational Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China
  • [ 64 ] [Liu G.-H.]Aging Biomarker Consortium, Beijing, 100101, China
  • [ 65 ] [Bao Y.]CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 66 ] [Bao Y.]National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 67 ] [Bao Y.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 68 ] [Zhang W.]CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing, 100101, China
  • [ 69 ] [Zhang W.]University of Chinese Academy of Sciences, Beijing, 100049, China
  • [ 70 ] [Zhang W.]Sino-Danish College, University of Chinese Academy of Sciences, Beijing, 101408, China
  • [ 71 ] [Zhang W.]Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, 100101, China
  • [ 72 ] [Zhang W.]Aging Biomarker Consortium, Beijing, 100101, China

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Source ：

Nucleic Acids Research

ISSN： 0305-1048

Year： 2024

Issue： D1

Volume： 52

Page： D909-D918

1 6 . 7 0 0

JCR@2023

CAS Journal Grade：2

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ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 2

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