The　relationship　between　the　flow　pattern　evolution　and　performance　of　oscillating　feedback　microreactors　(OFMs)　for　the　synthesis　of　ZIF-67　nanoparticles　was　investigated　by　a　photomicrography　technique.　Accordingly,　an　oscillating　feedback　microreactor　(OFM)　with　an　optimized　structure　was　identified　for　high-throughput　ZIF-67　production.　By　varying　the　experimental　conditions　(i.e.,　flow　rate,　aging　time,　precursor　concentration　[Co2+],　solvent,　and　cobalt　source),　the　average　size　of　ZIF-67　products　can　be　adjusted　(from　16　to　294　nm)　with　narrow　particle　size　distribution　(geometric　standard　deviation:　1.08-1.14)　as　well　as　with　controllable　morphology　(sphere　or　rhombic　dodecahedron).　The　maximum　total　flow　rate　can　reach　160　mL/min,　indicating　that　a　high-throughput　synthesis　of　ZIF-67　is　achieved.　The　screening　method　can　be　extended　to　optimize　other　microreactors,　and　the　resulting　OFMs　can　be　applied　to　produce　other　kinds　of　nanoparticles.