T-2　toxin　(T-2),　one　of　the　most　toxic　mycotoxins,　has　drawn　extensive　attention　due　to　its　universality　and　persistence　in　food　and　the　environment.　In　this　study,　a　novel　magnetic　ZnO/CaFe2O4　nanocomposite　with　a　p-n　based　Z-scheme　heterojunction　was　successfully　constructed　by　a　hydrothermal　method　for　efficient　photodegradation　of　T-2　toxin.　The　optimal　cubic　structure　of　ZnO/CaFe2O4　endows　it　with　excellent　photocatalytic　efficiency　in　removing　T-2　toxin,　such　that　near-total　degradation　was　achieved　with　an　exceptionally　high　mineralization　value　(64　%)　after　180　min　of　UV　radiation.　This　efficacy　was　attributed　not　only　to　the　abundant　reaction　sites　on　the　binary　composites,　but　also　its　Z-scheme　heterojunction　promoting　the　electron-hole　(e−-h+)　separation　and　hence　favors　redox　processes.　The　[rad]OH　played　a　major　role　in　the　photodegradation,　and　the　decomposition　pathway　of　T-2　was　proposed　based　on　the　results　of　UHPLC-Q-TOF-MS/MS　data　and　density　functional　theory　(DFT)　calculations.　This　work　provided　a　green　approach　for　removing　the　refractory　natural　pollutants.　©　2024　Elsevier　B.V.