• Complex
  • Title
  • Keyword
  • Abstract
  • Scholars
  • Journal
  • ISSN
  • Conference
成果搜索

author:

Cheng, K. (Cheng, K..) [1] | Zhang, J. (Zhang, J..) [2] | Ye, L.-Y. (Ye, L.-Y..) [3] | Lin, M.-H. (Lin, M.-H..) [4] | Ding, X.-Y. (Ding, X.-Y..) [5] | Zheng, X.-E. (Zheng, X.-E..) [6] | Zhou, X.-F. (Zhou, X.-F..) [7]

Indexed by:

Scopus

Abstract:

Background: Malnutrition is linked to a higher risk of unfavorable outcomes in various illnesses. The present investigation explored the correlation between inadequate nutritional condition and outcomes in older individuals diagnosed with hyperlipidemia. Methods: The geriatric nutritional risk index (GNRI) was used to evaluate the nutritional status. All patients were divided into two groups according to GNRI. A Kaplan-Meier analysis was used to assess the survival rates of different groups at risk of malnutrition. In addition, GNRI was used in COX proportional risk regression models to evaluate its predictive effect on both overall mortality and cardiovascular mortality among patients with hyperlipidemia. Furthermore, the study employed restricted cubic splines (RCS) to examine the nonlinear correlation between GNRI and mortality. Results: The study included 4,532 elderly individuals diagnosed with hyperlipidemia. During a median follow-up duration of 139 months, a total of 1498 deaths from all causes and 410 deaths from cardiovascular causes occurred. The Kaplan-Meier analysis demonstrated significantly poorer survival among individuals at risk of malnutrition, as indicated by the GNRI. In the malnutrition risk group, the modified COX proportional hazards model revealed that a decrease in GNRI was associated with a higher risk of all-cause mortality (HR=1.686, 95% CI 1.212-2.347) and cardiovascular mortality (HR=3.041, 95% CI 1.797-5.147). Furthermore, the restricted cubic splines revealed a non-linear association between GNRI and both all-cause mortality and cardiovascular mortality (p-value for non-linearity = 0.0039, p-value for non-linearity=0.0386). Conclusions: In older patients with hyperlipidemia, lower levels of GNRI are associated with mortality. The GNRI could potentially be used to predict all-cause mortality and cardiovascular mortality. © The Author(s) 2024.

Keyword:

All-cause mortality Cardiovascular mortality Geriatric Nutrition Risk Index Hyperlipidemia Older adults

Community:

  • [ 1 ] [Cheng K.]Shengli Clinical Medical College of Fujian Medical University, Fujian, Fuzhou, 350001, China
  • [ 2 ] [Cheng K.]The Fourth Department of Intensive Care Unit, Fuzhou University Affiliated Provincial Hospital, Fujian, Fuzhou, 350001, China
  • [ 3 ] [Zhang J.]Second Department of Infectious Disease, Shanghai Fifth People’s Hospital of Fudan University, Shanghai, 200240, China
  • [ 4 ] [Ye L.-Y.]Medical Intensive Care Unit, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, Zhangzhou, 363000, China
  • [ 5 ] [Lin M.-H.]The School of Clinical Medicine Department, Fujian Medical University, Fujian, Fuzhou, 350001, China
  • [ 6 ] [Ding X.-Y.]Shengli Clinical Medical College of Fujian Medical University, Fujian, Fuzhou, 350001, China
  • [ 7 ] [Ding X.-Y.]The Fourth Department of Intensive Care Unit, Fuzhou University Affiliated Provincial Hospital, Fujian, Fuzhou, 350001, China
  • [ 8 ] [Zheng X.-E.]Shengli Clinical Medical College of Fujian Medical University, Fujian, Fuzhou, 350001, China
  • [ 9 ] [Zheng X.-E.]The Fourth Department of Intensive Care Unit, Fuzhou University Affiliated Provincial Hospital, Fujian, Fuzhou, 350001, China
  • [ 10 ] [Zhou X.-F.]Shengli Clinical Medical College of Fujian Medical University, Fujian, Fuzhou, 350001, China
  • [ 11 ] [Zhou X.-F.]The Fourth Department of Intensive Care Unit, Fuzhou University Affiliated Provincial Hospital, Fujian, Fuzhou, 350001, China
  • [ 12 ] [Zhou X.-F.]Fujian Provincial Key Laboratory of Emergency Medicine, Fujian, Fuzhou, 350001, China

Reprint 's Address:

Email:

Show more details

Related Keywords:

Source :

BMC Geriatrics

ISSN: 1471-2318

Year: 2024

Issue: 1

Volume: 24

3 . 4 0 0

JCR@2023

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

Affiliated Colleges:

Online/Total:172/10051624
Address:FZU Library(No.2 Xuyuan Road, Fuzhou, Fujian, PRC Post Code:350116) Contact Us:0591-22865326
Copyright:FZU Library Technical Support:Beijing Aegean Software Co., Ltd. 闽ICP备05005463号-1