Hydrogen-bonded　organic　frameworks　(HOFs)　hold　significant　promise　for　catalytic　applications.　However,　the　collapse　of　pores　upon　solvent　removal　significantly　restricts　the　utility　of　HOFs　in　photocatalytic　processes　for　energy　production　and　storage.　This　work　describes　HOF-based　catalysis　with　a　stable　pore　structure　and　efficient　catalytic　activity　that　has　been　designed　and　tested　for　CO2　photo-reduction　in　pure　water.　In　this　system,　based　on　HOFs,　the　1,3,6,8-tetra(4-carboxyphenyl)pyrene　(H(4)TBAPy)　molecules　segment　the　large　pore　spaces　into　multiple　domains.　These　molecules,　anchored　to　the　HOF　via　strong　CH　&　ctdot;pi　interactions,　act　as　rigid　auxiliary　linkers,　notably　improving　the　structural　stability　within　the　HOF.　Additionally,　the　incorporation　of　electron-rich　H(4)TBAPy　molecules　expedited　electron　transport　within　the　HOF,　markedly　enhancing　its　catalytic　activity.　This　work　provides　a　new　strategy　for　designing　stable　and　high-performance　HOF　photocatalysts.