5-Hydroxymethylfurfural　(HMF)　is　a　widely　used　biomass　platform　chemical　that　plays　a　crucial　role　in　bridging　biomass　and　fossil　resources.　Electrocatalytic　oxidation　of　HMF　provides　an　efficient　way　to　obtain　high-value-added　biomass-derived　chemicals,　among　which　the　intermediate　product　5-formyl-2-furan　carboxylic　acid　(FFCA)　has　attracted　considerable　attention.　However,　the　weak　adsorption　ability　of　monometallic　nickel　oxide　(NiOx)　to　HMF　in　neutral　electrolyte　restricts　its　further　development,　resulting　in　low　HMF　conversion　and　FFCA　yield.　In　this　study,　we　successfully　constructed　a　novel　nickel　oxide-platinum　oxide　hybrid　catalyst　supported　on　carbon　felt　(NiOx-PtOx/CF),　which　exhibits　an　optimized　adsorption　ability　of　HMF,　leading　to　the　outstanding　FFCA　yield　up　to　77　%　in　the　neutral　media.　The　high　activity　of　the　NiOx-PtOx/CF　catalyst　can　be　attributed　to　the　redistribution　of　the　electrons　and　the　optimization　of　the　electronic　structure　on　the　Ni　active　site　due　to　the　introduction　of　PtOx　on　NiOx　nanosheets.　This　study　offers　valuable　insights　for　the　design　of　efficient　multicomponent　electrocatalysts　for　electrocatalytic　biomass　refinery　systems.　©　2024　Wiley-VCH　GmbH.