The　heavy-metal　contamination　of　aquatic　environments　presents　imminent　threat.　Herein,　we　report　a　class　of　dual-heteroatomic　conjugated　microporous　poly(aniline)s　showing　high-affinity　separation　performance　toward　heavy　metals.　The　prepared　keto-CMPA　shows　monolayer　adsorption　capacity　for　Hg　(II)　as　high　as　980　mg　g(-1)　according　to　the　Langmuir　model,　and　ultra-rapid　kinetic　with　h　reaching　30.41　mg　g(-1)　that　could　be　described　by　the　pseudo-second-order　model.　It　maintains　excellent　stability　across　six　reuses　under　harsh　conditions,　and　furthermore　demonstrates　ultradeep　separation　efficiency　that　could　adsorb　almost　all　of　heavy　metals　to　ppb　level　with　low　usage.　For　further　industrialization,　a　competent　adsorption　device　was　developed　to　remove　heavy　metals　down　to　1　ppb　with　a　remarkable　breakthrough　over　20,000　BV.　Characterizations　and　DFT　calculation　showed　that　the　triangular　synergistic　region　formed　by　the　N-O-sites　in　the　singular　CMPA　structure　provided　a　feasible　binding　energy　to　enable　the　above　impressive　performance.