Background　Pre-frailty　is　a　window　of　opportunity　for　frailty　reversal　and　can　be　enhanced　by　multicomponent　exercise.　The　Lifestyle-integrated　Functional　Exercise　(LiFE)　program　may　be　a　promising　alternative　to　overcome　traditional　exercise　barriers.　The　latest　advancements　in　mobile　health　(mHealth)　technology　have　enabled　individuals　to　retain　the　advantages　of　supervised　exercise　training　within　group　settings　while　providing　exercise　programs　that　can　be　accessed　and　completed　at　home.　This　study　aims　to　assess　the　feasibility,　acceptability,　and　primary　efficacy　of　the　PF-Life　program,　which　is　the　Lifestyle-Integrated　Functional　Exercise　program　for　Pre-Frail　supported　by　an　mHealth　platform.　Methods　Sixteen　pre-frail　adults　aged　＞=　65　years　were　recruited　from　five　community　health　centers　in　Fuzhou,　China.　All　participants　were　prescribed　the　PF-Life　program　by　geriatricians　using　the　mhealth　platform　(web-based　portal).　Participants　engaged　in　the　customized　exercises　program　following　in-app　video　instructions　and　feedback　on　the　mhealth　platform　(smartphone　application).　Physical　activity　(PA)　and　sedentary　behavior　(SB)　were　registered　daily　through　wearable　devices.　Study　endpoints　were　feasibility　(retention　rate,　compliance　rate,　adverse　events),　usability　(system　usability　scale),　acceptability　(qualitative　interviews),　changes　in　physical　function　(timed　up　and　go　(TUG),　handgrip　strength　(HGS),　and　30-second　chair　rise　tests),　PA　and　SB.　Results　The　intervention　was　feasible,　88%　of　participants　adhered　completely　to　the　study　protocol,　and　95%　had　completed　at　least　75%　of　the　prescribed　experimental　duration.　System　usability　was　high　(85　out　of　100　best　imaginable).　Changes　were　observed　from　baseline　to　follow-up　for　total　HGS　(21.41　+/-　6.38　vs.　24.12　+/-　6.62　kg,　P　＜　0.05,　d　=　0.714),　TUG　(8.23　+/-　1.33　vs.　7.48　+/-　2.01　s,　P　＜　0.01,　d　=　1.647)　and　30-second　chair　rise　test　(17.13　+/-　4.3　vs.　20.04　+/-　4.54　repetitions,　P　＜　0.01,　d　=　0.94).　In　addition,　SB　decreased　by　a　mean　of　33　min/day　(P　＜　0.01),　and　low　physical　activity　increased　by　31　min/day　(P　＜　0.01).　No　adverse　events　occurred.　The　majority　of　participants　found　the　PF-Life　program　to　be　straightforward,　adaptable,　and　easily　integrable　into　their　daily　routines.　Conclusions　Preliminary　studies　have　demonstrated　that　the　PF-life　program　exhibits　good　compliance,　safety,　and　usability　for　the　pre-frail　elderly　population.　Large-scale　randomized　controlled　trials　are　required　to　ascertain　its　long-term　effectiveness.