Synthesis of C-N or C-C Spiroindolines via Rearrangement Coupling Reaction - Details

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author：

Liu, X. (Liu, X..) ^[1] | Qiao, P. (Qiao, P..) ^[2] | Chen, H. (Chen, H..) ^[3] | Gao, Y. (Gao, Y..) ^[4]

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Abstract：

Herein,　we　report　a　general　approach　to　effectively　construct　C-N　or　C-C　spiroindolines　using　tetrahydro-β-carbolines　as　starting　materials　via　a　rearrangement　coupling　reaction.　This　method　is　characterized　by　its　operational　simplicity　and　mild　conditions.　Notably,　a　wide　range　of　anilines　and　indoles　are　suitable　for　this　intermolecular　coupling,　yielding　the　corresponding　C-N　or　C-C　spiroindolines　in　good　to　excellent　yields.　©　2024　American　Chemical　Society.

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[ 1 ] [Liu X.]Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350116, China
[ 2 ] [Qiao P.]Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350116, China
[ 3 ] [Chen H.]Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350116, China
[ 4 ] [Gao Y.]Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350116, China
[ 5 ] [Chen H.]Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fujian, Fuzhou, 350116, China

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Organic Letters

ISSN： 1523-7060

Year： 2024

Issue： 45

Volume： 26

Page： 9759-9763

4 . 9 0 0

JCR@2023

CAS Journal Grade：1

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ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 3

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