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author：

Chen, Y. (Chen, Y..) [1] | Li, B. (Li, B..) [2] | Ge, L. (Ge, L..) [3] | Cai, F. (Cai, F..) [4] | Tang, D. (Tang, D..) [5] | Yao, L. (Yao, L..) [6]

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Scopus

Abstract：

An　innovative　signal-transduction　tag　with　glucose-doped　calcium　carbonate　nanospheres　was　utilized　as　the　label　of　a　secondary　antibody　to　design　a　nano-labelled　immunosorbent　assay　(NLISA)　of　a　carcinoembryonic　antigen.　The　signal　was　achieved　on　a　personal　glucometer　via　the　released　glucose　molecules　from　the　nanospheres　under　acidic　conditions　after　formation　of　the　sandwiched　immune　complexes.　The　enzyme　and　the　spectrometer　in　the　conventional　enzyme-linked　immunosorbent　assay　(ELISA)　were　replaced　by　a　glucose-doped　calcium　carbonate　nanosphere　and　a　glucometer.　©　The　Royal　Society　of　Chemistry　and　the　Centre　National　de　la　Recherche　Scientifique　2024.

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  • [ 1 ] [Chen Y.]Pathology Department, Fujian Maternity and Child Health Hospital, Fujian Obstetrics and Gynecology Hospital, Fujian, Fuzhou, 350001, China
  • [ 2 ] [Li B.]Jiangsu Province Engineering Research Center of Traditional Chinese Medicine Health Preservation, Nanjing University of Chinese Medicine, Jiangsu, Nanjing, 210000, China
  • [ 3 ] [Ge L.]Jiangsu Province Engineering Research Center of Traditional Chinese Medicine Health Preservation, Nanjing University of Chinese Medicine, Jiangsu, Nanjing, 210000, China
  • [ 4 ] [Cai F.]College of Life Sciences, Fujian Normal University, Fujian, Fuzhou, 350117, China
  • [ 5 ] [Tang D.]Key Laboratory of Analytical Science for Food Safety and Biology, MOE & Fujian Province, Department of Chemistry, Fuzhou University, Fuzhou, 350108, China
  • [ 6 ] [Yao L.]Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, College of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fujian, Fuzhou, 350122, China

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Source ：

New Journal of Chemistry

ISSN： 1144-0546

Year： 2024

Issue： 48

Volume： 48

Page： 20246-20250

2 . 7 0 0

JCR@2023

CAS Journal Grade：4

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ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 1

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