Introduction　Patients　with　knee　osteoarthritis　are　at　a　higher　risk　of　falls　compared　to　healthy　individuals,　thereby　increasing　the　likelihood　of　accidental　injury.　Resistance　training　is　an　important　strategy　for　managing　knee　osteoarthritis.　Although　some　studies　suggest　that　blood　flow　restriction　training　combined　with　low-load　resistance　training　(LL-BFRT)　is　a　beneficial　treatment　approach,　its　effect　on　fall　risk　and　balance　function　in　patients　with　knee　osteoarthritis　remains　unclear.　We　aim　to　conduct　a　randomised　controlled　trial　to　assess　the　effectiveness　of　combined　training　in　reducing　fall　risk　and　improving　function　in　patients　with　knee　osteoarthritis.Methods　and　analysis　We　will　conduct　a　single-blind　pilot　randomised　controlled　trial　involving　patients　with　knee　osteoarthritis.　98　patients　will　be　randomly　assigned　to　either　the　LL-BFRT　group　or　the　low-load　resistance　training　(LL-RT)　group,　with　a　1:1　allocation　ratio.　Both　groups　will　undergo　a　4-week　intervention.　Follow-up　assessments　will　be　conducted　at　baseline,　4　weeks,　16　weeks,　28　weeks　and　52　weeks.　The　primary　outcome　will　be　the　measurement　of　the　fall　risk　stability　index　and　overall　stability　index　using　the　Biodex　Balance　System.　Secondary　outcomes　include　the　Numerical　Rating　Scale,　the　Western　Ontario　and　McMaster　Universities　Osteoarthritis　Index,　the　30　s　Chair　Stand　Test,　proprioception　testing,　the　Timed　Up　and　Go　Test,　the　Short　Form-36　scores,　compliance　and　adverse　events.　Intention-to-treat　principles　will　be　applied　in　data　analysis.Ethics　and　dissemination　This　study　has　been　approved　by　the　Ethics　Review　Committee　of　the　First　Hospital　of　Quanzhou　Affiliated　Fujian　Medical　University　(2024-K161).　The　results　of　the　study　will　be　disseminated　through　peer-reviewed　publications.Trial　registration　number　ChiCTR2400087829.