Upcycling　of　NO　into　NH3　provided　a　win-win　strategy　for　NO　purification　and　NH3　production.　In　this　work,　we　reported　an　approach　for　NH3　production　via　photo-assisted　thermalcatalytic　NO　and　H2O　reduction　by　CO　at　low　temperature　and　atmospheric　pressure.　Herein,　a　Pd/TiO2　model　catalyst　with　electron-enriched　Pd　and　oxygen　vacancies　dual　active　sites　was　applied.　The　results　showed　that　full　NO　conversion　was　realized　only　at　120　°C,　and　a　beyond　55.0%　NH3　selectivity　could　be　obtained　below　180　°C　over　Pd/TiO2.　A　series　of　collective　spectroscopic　and　theoretical　investigations　revealed　that　CO　adsorbed　at　Pd　site　and　H2O　dissociated　at　interfacial　oxygen　vacancies　would　first　interact　to　in　situ　generate　active　*H　species,　and　then　NO　also　adsorbed　at　interfacial　oxygen　vacancies　was　gradually　hydrogenated　by　*H　to　produce　NH3.　Light　irradiation　further　reinforced　this　process　by　promoting　oxygen　vacancies　formation　and　electron　transfer　for　enhancing　CO　and　NO　activation　and　H2O　dissociation.　This　work　provides　a　valuable　insight　into　NH3　production　via　photothermal　catalytic　NO　and　H2O　reduction　by　CO.　©　2025　Elsevier　B.V.