Lithium-sulfur　batteries　(LSBs)　are　a　promising　candidate　for　next-generation　energy　storage　solutions.　However,　challenges　such　as　the　shuttling　effect　and　sluggish　Li-S　reaction　kinetics　of　lithium　polysulfides　hinder　their　practical　application.　In　this　work,　we　present　a　mixed-phase　heterostructure　comprising　Co0.85Se　and　MoSe2,　supported　on　nitrogen-doped　carbon　polyhedrons　(NCP),　as　an　effective　sulfur　host　in　the　LSB　cathode.　Through　a　combination　of　theoretical　calculations　and　experimental　validation,　we　demonstrate　that　the　Co0.85Se-MoSe2　heterointerface　significantly　enhances　electron　transfer　efficiency,　thereby　boosting　the　overall　reaction　kinetics　of　the　sulfur　cathode.　As　a　result,　the　Co0.85Se-MoSe2/NCP/S　electrodes　exhibit　initial　specific　capacities　exceeding　1500　mAh　g−1　at　0.1　C　and　retain　666　mAh　g−1　at　3　C,　with　a　capacity　fade　rate　of　0.044%　per　cycle　over　500　cycles　at　1.0　C.　Notably,　even　at　a　high　sulfur　loading　of　3　mg　cm−2　and　a　reduced　electrolyte　volume　of　6.7　μL　mgS−1,　the　Co0.85Se-MoSe2/NCP/S　electrodes　maintain　a　capacity　of　432　mAh　g−1　after　100　cycles　at　0.2　C.　©　2025　Science　Press　and　Dalian　Institute　of　Chemical　Physics,　Chinese　Academy　of　Sciences