Enhanced peroxidase-like nanozyme: copper-poly(tannic acid) for advanced colorimetric assay of total antioxidant capacity - Details

author：

Chen, Y. (Chen, Y..) ^[1] | Zhang, Z. (Zhang, Z..) ^[2] | Ouyang, Y. (Ouyang, Y..) ^[3] | Reheman, A. (Reheman, A..) ^[4] | Jiang, B. (Jiang, B..) ^[5]

Indexed by：

Scopus

Abstract：

The　assessment　of　total　antioxidant　capacity　(TAC),　a　critical　marker　of　food　quality　in　terms　of　antioxidant　efficacy,　has　garnered　considerable　attention　in　human　health　management.　The　development　of　an　in　situ　technique　that　does　not　require　complex　apparatus　can　facilitate　accurate　and　rapid　TAC　detection.　Herein,　we　developed　a　specific　and　sensitive　colorimetric　assay　to　evaluate　the　TAC　of　fruit　juices　using　the　red-green-blue　(RGB)　model.　We　synthesized　a　copper-poly(tannic　acid)　(Cu-PTA)　coordination　polymer　that　exhibits　enhanced　peroxidase　(POD)-like　activity　in　the　presence　of　H2O2.　This　Cu-PTA　nanozyme,　along　with　H2O2,　enhances　the　conversion　of　the　colorless　compound　3,3′,5,5′-tetramethyl-benzidine　(TMB)　into　a　visually　perceptible　oxTMB　product.　This　chromogenic　reaction　is　suppressed　in　the　presence　of　antioxidants,　such　as　ascorbic　acid　(AA).　This　colorimetric　assay　achieved　a　limit　of　detection　of　0.06　μM　across　a　concentration　range　of　0.90-5.40　μM　for　AA.　Our　findings　enable　the　development　of　nanozymes　for　convenient　in　situ　TAC　analysis　to　assess　the　nutritional　value　of　food　items.　©　2025　The　Royal　Society　of　Chemistry.

Keyword：

Community：

[ 1 ] [Chen Y.]Fujian Key Laboratory of Toxicant and Drug Toxicology, Ningde Normal University, Fujian, Ningde, China
[ 2 ] [Chen Y.]Medical School, Ningde Normal University, Fujian, Ningde, China
[ 3 ] [Zhang Z.]Fujian Key Laboratory of Toxicant and Drug Toxicology, Ningde Normal University, Fujian, Ningde, China
[ 4 ] [Zhang Z.]Medical School, Ningde Normal University, Fujian, Ningde, China
[ 5 ] [Zhang Z.]Department of Chemistry, Fuzhou University, Fujian, Fuzhou, China
[ 6 ] [Ouyang Y.]Fujian Key Laboratory of Toxicant and Drug Toxicology, Ningde Normal University, Fujian, Ningde, China
[ 7 ] [Ouyang Y.]Medical School, Ningde Normal University, Fujian, Ningde, China
[ 8 ] [Reheman A.]Fujian Key Laboratory of Toxicant and Drug Toxicology, Ningde Normal University, Fujian, Ningde, China
[ 9 ] [Reheman A.]Medical School, Ningde Normal University, Fujian, Ningde, China
[ 10 ] [Jiang B.]Medical School, Ningde Normal University, Fujian, Ningde, China
[ 11 ] [Jiang B.]Yunnan Key Laboratory of Screening and Research on Anti-pathogenic Plant Resources from Western Yunnan, Dali, China

Reprint 's Address：

Email：

Show more details

Related Keywords：

Source ：

RSC Advances

ISSN： 2046-2069

Year： 2025

Issue： 15

Volume： 15

Page： 11401-11408

3 . 9 0 0

JCR@2023

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count：

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 0

Affiliated Colleges：

Get Fulltext

DOI Library Discovery Baidu Scholar Search SCOPUS

Type
Departments

All Years Choose Year From to