Metal-organic-frameworks　(MOFs),　consisting　of　various　and　flexible　metal　ions/clusters　and　organic　ligands,　represent　an　important　class　of　multifunction　materials.　However,　some　MOFs　suffer　from　their　instability　for　specific　applications.　In　the　present　study,　the　luminescent　properties　and　structure　evolution　of　lanthanide-based　MOFs　(Eu-MOF　and　Tb-MOF)　are　systemically　investigated　up　to　∼　15　GPa.　The　luminescence　of　Eu-MOF　and　Tb-MOF,　originating　from　the　energy　transfer　process　of　Eu3+　and　Tb3+　ions,　show　linear　red　shifts　upon　compression,　holding　a　promise　for　pressure　sensor　application.　The　underlying　mechanism　is　that　the　luminescence　of　Eu3+　and　Tb3+　ions　are　mostly　sensitive　to　the　local　environment　rather　than　the　symmetry　of　the　framework.　Thus,　the　luminescent　properties　of　the　Eu-MOF　and　Tb-MOF　are　preserved　in　their　degraded　counterparts,　even　undergoing　the　triclinic-to-triclinic　isostructure　phase　transition　at　∼　4　GPa.　Furthermore,　their　compressibility　is　comparable　with　the　typical　solid　pressure　transmitting　medium　(PTM)　of　NaCl.　In　addition,　a　pressure-induced　softening　effect　is　discovered　in　the　degraded　MOFs,　which　further　alleviates　the　indispensable　hardening　effect　of　PTM　at　high　pressures.　Consequently,　these　soft　degraded　MOFs　can　serve　as　PTM　and　pressure　sensors　simultaneously,　which　will　facilitate　the　diamond　anvil　cell　experiment　in　the　future.　©　2025