Indexed by:
Abstract:
In order to improve the stability and solubility of Monascus pigment, nanocapses were prepared by composite coagulation method with gelatin and gum acacia as wall materials. The wall material ratio and pH conditions of the complex coacervation reaction were determined by measuring the turbidity curve, particle size and PDI of the soluble complex stage. The results showed that the ratio of gelatin and gum arabic was 1:1 and the pH was 4.7, which was most beneficial to the composite cohesion reaction of wall materials. On this basis, the effects of wall material concentration, core material concentration, and curing agent concentration on nanocapsules were explored. The results showed that the most uniform and stable nano-capsules could be obtained when the wall material concentration was 7.5 mg/mL, the core material concentration was 7.5 mg/mL, the Monascus pigment content was 15 mg/mL, the curing agent addition was 3 mg/mL, and the volume fraction of the emulsifier addition was 0.5%. Under these conditions, the encapsulation rate of nanocapsules was 95.46%, the mean particle size was 99.81 nm, the PDI was 0.174, the zeta potential was-15.56 mV, and the solubility reached 95%. The photostability, storage stability, and in vitro release activity of the nanocapsules were characterized. The results showed that the storage stability and photostability of Monascus pigment were significantly improved. The degradation kinetics of red pigment and orange pigment in nanocapsules followed a first-order degradation model, while the degradation kinetics of yellow pigment followed a zero-order degradation model. The fitting data showed that the half-life of the pigment nanocapsules was significantly prolonged and the light stability was improved. In addition, the moascus pigment nanocapsules possessed certain intestinal targeted release function, with less release in simulated gastric fluid and greater release in simulated intestinal fluid, indicating that the nano-embedding system could improve the bioavailability of Monascus pigments. © 2025 Chinese Institute of Food Science and Technology. All rights reserved.
Keyword:
Reprint 's Address:
Email:
Version:
Source :
Journal of Chinese Institute of Food Science and Technology
ISSN: 1009-7848
Year: 2025
Issue: 6
Volume: 25
Page: 214-224
Cited Count:
SCOPUS Cited Count:
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 1
Affiliated Colleges: