Although　the　advanced　oxidation　processes　(AOP)　based　on　the　activation　of　persulfate　over　carbon　materials　to　degrade　organic　pollutants　has　attracted　enormous　attention,　the　surface　engineering　of　carbon　catalysts　is　still　desired　to　boost　their　performance.　Meanwhile,　the　synthesis　of　the　nitrogen　(N)-doped　carbon　commonly　relies　on　an　excessive　external　N　source,　which　not　only　causes　the　waste　of　raw　materials　but　also　makes　it　difficult　to　realize　the　good　distribution　of　N　dopants.　Herein,　N-doped　porous　graphene-like　carbon　was　synthesized　using　a　nucleobase　as　endogenous　N　precursors,　during　which　zinc　nitrate　was　adopted　to　modulate　the　surface　structures　and　the　chemical　state　of　each　element.　The　optimal　sample　NG-5　was　highly　adsorptive　and　effective　for　the　activation　of　peroxydisulfates　(PDS)　to　degrade　tetracycline　(TC),　which　could　also　work　in　a　relatively　wide　pH　range　and　demonstrated　high　stability.　The　porous　structure　and　high　surface　area　facilitated　the　catalyst　to　expose　more　active　sites.　In-depth　studies　suggested　that　the　activation　of　PDS　followed　mixed　routes,　where　both　radical　and　nonradical　paths　made　notable　contributions.　Superoxide　radicals　and　singlet　oxygen　were　mainly　responsible　for　TC　degradation,　while　the　contribution　of　hydroxyl　and　sulfate　radicals　could　be　ignored.　©　2025　American　Chemical　Society