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author:

Zheng, Mi (Zheng, Mi.) [1] | Paulus, Yannis M. (Paulus, Yannis M..) [2]

Indexed by:

SCIE

Abstract:

Choroidal neovascularization (CNV) has been associated with a wide variety of chorioretinal disorders, which can cause vascular leakage, bleeding, and scar formation, leading to significant vision loss. The effective and precise detection of CNV is essential for optimal disease management. A classification system has been devised to categorize neovascularization according to its anatomical location. The system distinguishes three distinct types of neovascularization: type 1, type 2, and type 3. According to the exudative features of the new vessels, CNV can be divided into exudative and non-exudative categories. Each type of CNV exhibits unique features across various imaging modalities. The present study reviews contemporary imaging modalities employed in the detection of CNV, with a focus on the underlying mechanisms, their respective advantages and disadvantages, their typical clinical utilization, and the characteristic features of CNV that are discernible through these techniques. The exploration of novel promising imaging techniques for CNV detection including photoacoustic microscopy, AI, photothermal OCT, and functional fluorescent angiography is also performed.

Keyword:

Choroidal neovascularization Fluorescein angiography Functional fluorescein isothiocyanate Imaging techniques Indocyanine green angiography Optical coherence tomography Optical coherence tomography angiography Photoacoustic microscopy Photothermal OCT

Community:

  • [ 1 ] [Zheng, Mi]Johns Hopkins Univ, Wilmer Eye Inst, Dept Ophthalmol, Baltimore, MD 21287 USA
  • [ 2 ] [Paulus, Yannis M.]Johns Hopkins Univ, Wilmer Eye Inst, Dept Ophthalmol, Baltimore, MD 21287 USA
  • [ 3 ] [Paulus, Yannis M.]Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD 21287 USA
  • [ 4 ] [Zheng, Mi]Fuzhou Univ, Dept Ophthalmol, Affiliated Prov Hosp, Fuzhou 350001, Fujian, Peoples R China
  • [ 5 ] [Zheng, Mi]Fujian Med Univ, Dept Ophthalmol, Prov Clin Med Coll, Fuzhou 350001, Fujian, Peoples R China

Reprint 's Address:

  • [Paulus, Yannis M.]Johns Hopkins Univ, Wilmer Eye Inst, Dept Ophthalmol, Dept Biomed Engn, 600 N Wolfe St, Baltimore, MD 21287 USA

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Source :

EXPERIMENTAL EYE RESEARCH

ISSN: 0014-4835

Year: 2025

Volume: 259

3 . 0 0 0

JCR@2023

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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