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Abstract:
Unlike many other state-of-the-art transition-metal-catalyzed allylic substitutions, cobalt-catalyzed allylic substitution has received much less attention from synthetic chemists for a long time despite the fact that cobalt is an earth-abundant, low-cost and thus much more sustainable option as either a reagent or a catalyst in organic synthesis. Recently, there has been an upsurge in the use of cobalt catalysis in allylic functionalization reactions, including allylic substitution, nucleophilic allylation, and Heck-type allylic functionalization, to construct synthetically significant building blocks featuring a double bond available for diverse downstream synthetic manipulations. This review highlights the current development of cobalt catalysis in allylic functionalization with an in-depth discussion of the reaction scope and mechanistic insights.
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ORGANIC & BIOMOLECULAR CHEMISTRY
ISSN: 1477-0520
Year: 2020
Issue: 39
Volume: 18
Page: 7740-7750
3 . 8 7 6
JCR@2020
2 . 9 0 0
JCR@2023
ESI Discipline: CHEMISTRY;
ESI HC Threshold:160
JCR Journal Grade:1
CAS Journal Grade:3
Cited Count:
WoS CC Cited Count: 0
SCOPUS Cited Count: 24
ESI Highly Cited Papers on the List: 1 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 0
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