CoOx-MC　(MC　=　mesoporous　carbon),　with　CoOx　nanoparticles　of　ca.　25　nm　well　distributed　on　mesoporous　carbon,　was　synthesized　by　calcination　of　a　Co/polymer　framework　precursor　prepared　via　ion　exchange　between　Co2+　in　[Co(NH3)(6)](2+)　and　H+　in　the　polymeric　gel.　The　as-synthesized　CoOx-MC　exhibited　superior　performance　for　the　selective　oxidation　of　5-hydroxymethylfurfural　(5-HMF)　to　produce　2,5-furandicarboxylic　acid　(FDCA)　in　water　using　O-2　as　the　oxidant　at　80　degrees　C,　with　98.3%　of　5-HMF　converted　in　30　h　and　a　yield　of　95.3%　to　desirable　FDCA.　The　turnover　frequency　(TOF)　for　the　formation　of　FDCA　over　CoOx-MC　was　determined　to　be　2.22　h(-1),　a　performance　superior　to　those　non-noble　metal　catalysts　ever　reported　for　the　selective　oxidation　of　5-HMF　to　produce　FDCA.　This　study　not　only　provides　an　efficient,　cost-saving,　and　environmentally　friendly　catalytic　system　for　the　production　of　FDCA　from　5-HMF　but　also　highlights　the　great　potential　of　mesoporous　carbon　as　the　support　in　fabricating　highly　active　catalytic　systems.