Four　indium-based　heterometallic　metal-organic　frameworks　In3M(IMDC)(3)(NO3)(2)(H2O)(6)solvent　(2-M,　M　=　Mn,　Co,　Zn,　Mg,　H3IMDC　=　imidazole-4,5-dicarboxylic　acid)　have　been　made　under　solvothermal　conditions,　and　are　characterized　by　single-crystal　X-ray　diffraction　studies,　energy-dispersive　X-ray　spectroscopy,　infrared　spectroscopy,　thermogravimetric　analysis,　and　powder　X-ray　diffraction　analysis.　Structural　analysis　indicates　that　2-M　exhibit　3D　porous　frameworks　generated　by　linking　three　intersecting　1D　In-IMDC　helical　chains　with　different　M2+　ions.　Powder　X-ray　diffraction　studies　reveal　that　2-M　exhibit　good　thermal　and　water　stability.　Furthermore,　2-M　show　moderate　gas　adsorption　abilities　that　can　be　modulated　by　introducing　different　M2+　ions.　Finally,　the　solid-state　luminescent　emissions　of　2-M　at　room　temperature　are　also　elucidated.