A　novel　strategy　for　rapidly　fabricating　ionic　liquid　(IL)-bonded　multifunctional　monolithic　stationary　phase　has　been　developed　by　an　in-situ　polycondensation　of　urea-formaldehyde　(UF)　and　a　lab-made　acylamino-functionalized　IL　(1-acetylamino-propyl-3-methylimidazolium　bromide,　[AAPMIm]Br).　Two　polycondensation　processes　of　UF　with　1-amino-propyl-3-methylimidazolium　bromide　or　[AAPMIm]Br　were　evaluated.　Several　parameters　including　mass　ratio　of　urea-formaldehyde,　amount　of　[AAPMIm]Br,　polycondensation　time　and　reaction　temperature　were　optimized,　and　the　[AAPMIm]Br-bonded　monolithic　stationary　phase　could　be　rapidly　synthesized　in　10　min　with　a　satisfactory　permeability　and　mechanical　stability.　Used　for　pressurized　capillary　electrochromatography　(pCEC),　a　typical　hydrophilic　interaction　(HI)　retention　could　be　obtained　in　the　resultant　[AAPMIm]Br-bonded　monolith　when　the　content　of　acetonitrile　(ACN)　in　mobile　phase　exceeded　20%.　Multiple　retention　mechanisms　such　as　hydrophilic　interaction　(HI),　hydrogen　bond　(H-H),　anion-exchange　and　cation-exclude　interactions,　were　acheived　in　the　[AAPMIm]Br-bonded　monolith.　Various　polar　compounds　including　phenols,　benzoic　acid　and　its　homologues,　and　enkephalins　have　been　well　separated　and　thus　demonstrated　a　satisfactory　separation　performance　of　the　obtained　monolith.　A　facile　access　is　lighted　for　rapid　preparation　of　ionic　liquid-bonded　monoliths　with　multiple　retention　mechanisms　for　pCEC.　(C)　2016　Elsevier　B.V.　All　rights　reserved.