Thiosemicarbazides　and　their　metal　complexes　have　attracted　considerable　interest　because　of　their　biological　activities　and　their　flexibility,　which　allows　the　ligands　to　bend　and　rotate　freely　to　accommodate　the　coordination　geometries　of　various　metal　centres.　Discrete　copper(II)　and　cadmium(II)　complexes　have　been　prepared　by　crystallization　of　N-[2-(2-hydroxybenzoyl)hydrazinecarbonothioyl]　propanamide　(H3L)　with　Cu(CH3COO)(2)　or　Cd(NO3)(2)　in　a　dimethylformamide/methanol　mixed-solvent　system　at　room　temperature,　affording　the　complexes　di-mu-acetato-bis{mu(4)-1-[(2-oxidophenyl)carbonyl]-2-(propanamidomethanethioyl)hydrazine-1,2-diido}tetracopper(II)　dimethylformamide　disolvate,　[Cu-4(C11H10N3O3S)(2)(C2H3O2)(2)]center　dot　2C(3)H(7)NO,　(I),　and　bis{mu(2)-[(2-hydroxyphenyl)formamido](propanamidomethanethioyl)azanido}bis[(4,40-bipyridine)nitratocadmium(II)]　dihydrate,　[Cd-2(C11H12N3O3S)(2)(NO3)(2)(C10H8N2)(2)]center　dot　2H(2)O,　(II).　Complex　(I)　consists　of　four　Cu-II　cations,　two　mu(4)-bridging　trianionic　ligands　and　two　mu(2)-bridging　acetate　ligands,　while　complex　(II)　is　composed　of　two　Cd-II　cations,　two　mu(2)-bridging　monoanionic　ligands,　two　nitrate　ligands　and　two　4,4＇-bipyridine　ligands.　These　discrete　complexes　are　connected　by　hydrogen　bonds　and　van　der　Waals　interactions　to　form　a　three-dimensional　supramolecular　architecture.　Compared　with　(I),　the　phenolic　hydroxy　group　and　hydrazide　N　atom　of　the　thiosemicarbazide　ligand　of　(II)　are　not　involved　in　coordination　and　lead　to　a　binuclear　Cd-II　complex.　This　different　coordination　mode　may　be　attributed　to　the　larger　ionic　radius　of　the　Cd-II　ion　compared　with　the　Cu-II　ion.