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author:

Wang, Jianhua (Wang, Jianhua.) [1] (Scholars:王建华) | He, Chaolong (He, Chaolong.) [2] | Cheng, Niangmei (Cheng, Niangmei.) [3] | Yang, Qiu (Yang, Qiu.) [4] | Chen, Mingmao (Chen, Mingmao.) [5] (Scholars:陈名懋) | You, Lijun (You, Lijun.) [6] (Scholars:游力军) | Zhang, Qiqing (Zhang, Qiqing.) [7]

Indexed by:

EI Scopus SCIE

Abstract:

Single-wall carbon nanotubes (SWNTs) have attractive biochemical properties such as strong cell adhesion and protein absorption, which are very useful for a cell cultivation scaffold. In this study, collagen/SWNT-COOHs nanocomposite films composed of regenerated fish collagen and SWNT-COOHs (0, 0.5, 1.0 and 2.0 weight percent) were prepared by mixing solubilized pepsin-soluble collagen with solutions of SWNT-COOHs. Morphological observation by SEM indicated the homogenous dispersion of SWNT-COOHs in the collagen matrix. The application of FTIR confirmed that the process we applied to prepare the composites did not destroy the native structures of collagen and composites were crosslinked by D-ribose. The biocornpatibility was evaluated in vitro using SD rat bone marrow stem cells (BMSCs). Compared with films without transforming growth factor beta 1 (TGF-beta 1), films with TGF-beta 1 had superior performance on promotion of cell growth. Compared with pure collagen film with TGF-beta 1, SWNT-containing films might promote cellular functions by adsorbing more growth factors. In conclusion, the study suggested that the collagen/SWNT-COOHs nanocomposite films with TGF-beta 1 were expected to be useful scaffolds in cartilage tissue engineering.

Keyword:

Bone Marrow Stem Cells Carbon Nanotubes Cartilage Tissue Engineering Collagen

Community:

  • [ 1 ] [Wang, Jianhua]Fuzhou Univ, Inst Biomed & Pharmaceut Technol, Fuzhou 350002, Peoples R China
  • [ 2 ] [He, Chaolong]Fuzhou Univ, Inst Biomed & Pharmaceut Technol, Fuzhou 350002, Peoples R China
  • [ 3 ] [Cheng, Niangmei]Fuzhou Univ, Inst Biomed & Pharmaceut Technol, Fuzhou 350002, Peoples R China
  • [ 4 ] [Yang, Qiu]Fuzhou Univ, Inst Biomed & Pharmaceut Technol, Fuzhou 350002, Peoples R China
  • [ 5 ] [Chen, Mingmao]Fuzhou Univ, Inst Biomed & Pharmaceut Technol, Fuzhou 350002, Peoples R China
  • [ 6 ] [You, Lijun]Fuzhou Univ, Inst Biomed & Pharmaceut Technol, Fuzhou 350002, Peoples R China
  • [ 7 ] [Zhang, Qiqing]Fuzhou Univ, Inst Biomed & Pharmaceut Technol, Fuzhou 350002, Peoples R China
  • [ 8 ] [Wang, Jianhua]Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China
  • [ 9 ] [He, Chaolong]Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China
  • [ 10 ] [Cheng, Niangmei]Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China
  • [ 11 ] [Yang, Qiu]Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China
  • [ 12 ] [Chen, Mingmao]Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China
  • [ 13 ] [You, Lijun]Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China
  • [ 14 ] [Zhang, Qiqing]Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China
  • [ 15 ] [Zhang, Qiqing]Chinese Acad Med Sci, Peking Union Med Coll, Inst Biomed Engn, Tianjin 300192, Peoples R China

Reprint 's Address:

  • 王建华

    [Wang, Jianhua]Fuzhou Univ, Inst Biomed & Pharmaceut Technol, Fuzhou 350002, Peoples R China

Email:

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Source :

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

ISSN: 1533-4880

Year: 2015

Issue: 7

Volume: 15

Page: 4844-4850

1 . 3 3 8

JCR@2015

1 . 1 3 4

JCR@2019

JCR Journal Grade:3

CAS Journal Grade:4

Cited Count:

WoS CC Cited Count: 23

SCOPUS Cited Count: 24

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 5

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