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author:

Liu, Wei (Liu, Wei.) [1] (Scholars:刘薇) | Zhang, Lan (Zhang, Lan.) [2] (Scholars:张兰) | Fan, Liangbiao (Fan, Liangbiao.) [3] | Lin, Zian (Lin, Zian.) [4] (Scholars:林子俺) | Cai, Yimin (Cai, Yimin.) [5] | Wei, Zhenyi (Wei, Zhenyi.) [6] | Chen, Guonan (Chen, Guonan.) [7] (Scholars:陈国南)

Indexed by:

EI Scopus SCIE

Abstract:

In this paper, a convenient and self-assembled hollow fiber solvent-stir bar microextraction (HF-SSBME) device was developed, which could stir by itself. In the extraction process, the proposed device made the solvent "bar" not floating at the sample solution and exposing to air while organic solvents outside hollow fiber always wrapped with donor phase solvent, which reduced the vaporization of organic solvents. This design could improve the precisions and recoveries of experiments. For evaluating the device, seven anabolic steroids (prasterone, 5 alpha-androstane-3 alpha, 17 beta-diol, methandriol, 19-norandrostenediol, androstenediol, methyltestosterone and methandienone) were used as model analytes and extraction conditions such as type and volume of organic solvents, agitation speed, extraction time, extraction temperature and salt addition were studied in detail. Under the optimum conditions (15 mu L toluene, 40 degrees C, stirring at 750 rpm for 30 min with 1.5g sodium chloride addition in 20.0 mL donor phase), the linear ranges of anabolic steroids were 0.25-200 ng mL(-1) with gas chromatography-mass spectrometry. The limits of detection were lower than 0.10 ng mL(-1). The recoveries and precisions in spiked urine and hair samples were between 73.97-93.56% and 2.18-4.47% (n = 5). HF-SSBME method combined the intrinsical merits of hollow fiber with the superiority of the proposed self-stirring device which can be developed to two-phase, three-phase and in situ derivatization modes with wide prospect of application. Besides, the pedestal of this proposed device can be converted to fix stir bar in stir bar sorptive extraction (SBSE) method. (C) 2012 Elsevier B.V. All rights reserved.

Keyword:

Anabolic steroids Gas chromatography-mass spectrometry Hollow fiber solvent-stir bars microextraction (HF-SSBME) Sample preparation

Community:

  • [ 1 ] [Liu, Wei]Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China
  • [ 2 ] [Zhang, Lan]Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China
  • [ 3 ] [Fan, Liangbiao]Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China
  • [ 4 ] [Lin, Zian]Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China
  • [ 5 ] [Cai, Yimin]Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China
  • [ 6 ] [Wei, Zhenyi]Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China
  • [ 7 ] [Chen, Guonan]Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China
  • [ 8 ] [Liu, Wei]Fuzhou Univ, Sport Sci Res Ctr, Fuzhou 350002, Fujian, Peoples R China
  • [ 9 ] [Zhang, Lan]Fuzhou Univ, Sport Sci Res Ctr, Fuzhou 350002, Fujian, Peoples R China

Reprint 's Address:

  • 张兰

    [Zhang, Lan]Fuzhou Univ, Dept Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Anal & Detect Food Safety, Fuzhou 350002, Fujian, Peoples R China

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Source :

JOURNAL OF CHROMATOGRAPHY A

ISSN: 0021-9673

Year: 2012

Volume: 1233

Page: 1-7

4 . 6 1 2

JCR@2012

3 . 8 0 0

JCR@2023

ESI Discipline: CHEMISTRY;

JCR Journal Grade:1

CAS Journal Grade:2

Cited Count:

WoS CC Cited Count: 37

SCOPUS Cited Count: 38

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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