In　this　paper,　we　study　the　global　practical　output　regulation　problem　based　on　event-triggered　control　for　a　class　of　nonlinear　systems　with　nonlinear　exosystem.　We　first　develop　a　feedforward　event-triggered　control　law　and　prove　the　input-to-state　stability　of　the　closed-loop　system　by　viewing　the　sampling　error　and　the　steady　state　of　the　actuator　together　as　the　external　input.　Then,　based　on　the　high　gain　feedback　technique　and　a　well-defined　event-triggered　mechanism,　it　can　be　shown　that　the　ISS　gain　function　can　be　sufficiently　small,　and　hence　the　tracking　error　can　be　made　global　ultimately　bounded　with　an　arbitrarily　predefined　upper　bound.　Finally,　a　simulation　example　is　provided　to　illustrate　the　results.