Atomically　thin　wurtzite　ZnS　nanosheets　(NSs)　are　synthesized　via　photocatalytic　oxidation　exfoliation　of　ZnS(en)0.5　process　in　room　temperature　and　applied　in　piezocatalysis　for　the　first　time.　On　account　of　the　excellent　flexible,　high　piezoelectric　coefficient,　large　mechanical　energy　capture　area,　rich　and　efficient　catalytic　active　sites,　the　as-prepared　ZnS　shows　superior　piezocatalytic　performance　for　H2　production　from　H2O　without　any　co-catalyst　and　sacrificial　agent.　The　rate　of　H2　evolution　is　as　high　as　1.08　μmol　h−1　mg−1.　Furthermore,　this　work　would　can　not　only　enrich　the　high-efficiency　piezocatalytic　materials　system,　but　can　also　provide　a　new　idea　for　the　exploitation　of　piezocatalysts　with　excellent　performance　in　piezocatalytic　H2　evolution　from　pure　water.　©　2020　Elsevier　B.V.